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LVEF can be normal in the presence of impaired LV systolic function, since it does not reflect intrinsic myocardial contractility. 1 In addition, LVEF is highly load-dependent and suffers from significant intraobserver and interobserver variability. 2 Assessment of myocardial strain can potentially overcome many of the limitations of LVEF in .In the presence of global LV dysfunction, the LV pressure buildup will decrease and the LA pressure will increase which will decrease the rate of rise of MR jet velocity. This is the principle behind this method of assessing global LV function.
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